Pharmaceutically active copolymers, process for their preparation and pharmaceutical compositions containing them

摘要

The invention relates to new, pharmaceutically active copolymers with heparin-like activity, pharmaceutically acceptable salts thereof and a process for their preparation. The new copolymers comprise the units of the formula I <IMAGE> /I/ wherein X stands for hydrogen or methyl and Y is hydrogen, units of the formula III <IMAGE> /III/ optionally units of the formula II <IMAGE> /II/ wherein Z' is hydrogen, and chain terminating units, formed from the units of the formulae I, III and optionally II under the conditions of copolymerization, in a statistical arrangement, and the pharmaceutically acceptable salts thereof, which contain, in addition to the above chain-members, units of the formulae IV and/or V <IMAGE> /IV/ <IMAGE> /V/ wherein A