5-ALKYL-PIPERAZINYL-QUINOLINE DERIVATIVES

摘要

Quinoline compounds of the formula: in which: represents a group of the formula: in which: R' is hydrogen or methyl, R and R'' which are the same or different, each represents: hydrogen, (C1-C5) alkyl, (C1-C5) acyl haloacyl or aminoacyl, (C1-C3) alkylsulfonyl, or diethylphosphonyl; n is an integer form 1 to 4 inclusive; T is phenyl, halophenyl, trifluoromethylphenyl [(C1-C5) alkyl] phenyl, [(C1-C5) alkoxy] phenyl, or a five or six-membered heterocyclic radical containing one or two atoms selected from nitrogen and sulfur atoms optionally substituted by one or more (C1-C5) alkyl or (C1-C5) alkoxy. These compounds and physiologically tolerable acid addition salts thereof may be used a medicines especially in the treatment of disorders connected with hypoxemia and energetic metabolic insufficiency especially during cerebral aging.