| 摘要 |
Novel compounds of the formula I <IMAGE> in which R1 represents hydrogen or alkyl having 1 to 4 C atoms, R2 represents hydrogen, Cl, Br or CH3, R3 represents alkyl having 1 to 5 C atoms or alkenyl having 3-5 C atoms, the double bond not being situated on the C atom adjacent to the N, and R4 represents alkyl having 3 to 7 C atoms, cycloalkyl having 3-7 C atoms, adamantyl, phenyl which is optionally substituted one or more times by alkyl having 1 to 3 C atoms, alkoxy having 1 to 3 C atoms, alkylthio having 1 to 3 C atoms, CF3, OH, NO2, NH2, NH(alkyl having 1 to 3 C atoms) and/or N(alkyl having 1 to 3 C atoms)2, or phenyl which is fused to a non-aromatic 5- or 6-membered ring containing 1 or 2 O and/or S atoms, with the proviso that if R1 and R2 represent hydrogen and R3 represents CH3, R4 does not denote the tert-butyl group, and the acid addition salts of these compounds. These compounds have LH and PRL secretion-inhibiting and apomorphine-antagonistic actions.
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