发明名称 Local anesthetic mixture for topical application and method for obtaining local anesthesia
摘要 The present invention relates to pharmacological active preparations, especially local anesthetic preparations and deals with the problem of i a obtaining a solution of a local anesthetic agent in the form of its base, where the concentration is higher than otherwise possible. This problem has been dissolved according to the present invention thereby that one local anesthetic agent in the form of its base and as such having a melting point of 30 DEG to 50 DEG C., preferably prilocaine or tetracaine, is provided with one other local anesthetic agent in the form of its base and as such having a melting point of above 30 DEG C., preferably above 40 DEG C., preferably bensocaine, lidocaine, bupivacaine, mepivacaine, etidocaine or tetracaine which agents when brought and heated together form a homogenous oil having a melting of preferably below 40 DEG C., more preferably below 25 DEG C.
申请公布号 US4529601(A) 申请公布日期 1985.07.16
申请号 US19820411624 申请日期 1982.08.26
申请人 ASTRA LAKEMEDEL AKTIEBOLAG 发明人 BROBERG, BERNDT F. J.;EVERS, HANS C. A.
分类号 A61K45/06;A61K31/165;A61K31/245;A61K31/445;A61P25/02;(IPC1-7):A61K7/32;A61K9/12;A61K9/70 主分类号 A61K45/06
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