Oral anti-cancer compositions.

摘要

An orally-administrable pharmaceutical composition for the treatment of cancer comprising a coordination compound of platinum having the general formula (A)(B)Pt(X) (Y)trans(Z)2 in which A and B are the same or different and are each selected from ammine abd alkylamines or together represent a diaminocycloalkane, X and Y are the same or different and are selected from halide and pseudohalide or together represent cycloalkanedicarboxylate, with the provisos that when X and Y together represent cycloalkanedicarboxylate A and B do not represent ammine and/or alkylamine and when A and B together represent a diaminocyclohexane X and Y do not represent halide and/or pseudohalide, and the Z moieties are optional and are selected from halide and hydroxy, in association with a pharmaceutically-acceptable orally-administrable carrier therefor.