| 摘要 |
NEW MATERIAL:A polyphenol compound having the following characteristics. Appearance, brownish powder; melting point, 185-190 deg.C (decomposition); molecular weight, 20,400; elemental analysis, C 58.19, H 4.53, N 0.00, ash 1.33 (Na); peak of UV absorption spectrum, 280nm in methanol. USE:A carcinostatic agent. Useful as an excellent chemotherapeutic agent for cancer of warm-blooded animal such as man and domestic animals. PREPARATION:The dry powder of bark of the twig of Pterocarpus indicus willd is extracted by immersing in hydrated methanol for a night under stirring, filtered, extracted again with hydrated methanol for a night, and filtered. Both filtrates are joined together to obtain the extract liquid, which is concentrated under reduced pressure to remove methanol. The concentrated product is adsorbed with a column packed with Sephadex HL200, washed with water, and eluted with dioxane. The eluted active component is collected, concentrated under reduced pressure, and purifid to obtain the objective polyphenol compound. |
