| 摘要 |
PURPOSE:To diagnose air-passage occlusive lesions such as the bronchitis obliterans, bronchial carcinoma, etc. by adding a bodily fluid to the agglutination of lectin and human red blood cells and detecting the nature of the change that the lectin-affinity material in the bodily fluid gives on the agglutination. CONSTITUTION:Lectin, for example, furze (ulex europeaus) agglutinin or Lotus corniculatus Linn. var. japonicus Regel agglutinin and human red blood cells are brought into agglutination. The system consisting of a bodily fluid such as serum or the like diluted double double by a physiological salt soln. is added thereto in this stage to change the agglutination. The lectin-affinity material which is polysaccharide such as fucose or the like exhibiting the reactive specificness to lectin is contained in the bodily fluid of the brinchitis obliterans. More specifically, the bodily fluid is added to the agglutination reaction of the lectin and the human red blood cells to cause agglutination and the max. dilution times of the bodily fluid to intensify the agglutination are determined, by which the lectin-affinity material in the bodily fluid is detected. The presence or absence of the bronchitis obliterans, the detection of the ill condition thereof and the diagonsis of the prognosis are thus made possible. |
