| 摘要 |
<p>PENETRATING TOPICAL MEDICAMENT An improved topical medicament useful in treating athletic injuries or other painful subdermal conditions is provided which includes a penetrating solvent such as dimethylsulfoxide (DMSO) along with, in preferred forms, a corticosteroid (e.g., hydrocortisone acetate), a counterirritant/analgesic such as methyl salicylate, and one or more emulsifiers, a rubifacient and an alcoholic carrier. The medicaments hereof, when applied topically, are absorbed through the skin and serve to transport the corticosteroid and/or analgesic to a site of inflammation. The preferred salicylate component is converted to the analgesic salicyic acid and active metabolites in the bloodstream to serve as a pain killing agent (i.e., a prostaglandin inhibitor). The compositions hereof may be in the form of lotions, creams or aerosols, depending upon desired end use.</p> |
