| 摘要 |
New isoindolin-2-yl-guanidines and isoindolin-2-yl-aminoimidazolines of the general formula <IMAGE> (I) in which R1 and R2 can be identical or different and either hydrogen or a halogen, alkyl, or alkoxy, each with 1 to 4 carbon atoms, R3 and R4 can be identical or different and either a hydrogen or an alkyl with 1 to 4 carbon atoms, and R5, R6, R7, and R8 can be identical or different and either hydrogen or an alkyl with 1 to 4 carbon atoms, or in which R5 and R6 together represent the ethylene group, and their salts have an alpha -sympathomimetic and vasoconstrictive action that makes them appropriate as drugs for the treatment of hypotonic and rhinological states.
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