| 摘要 |
L-proline production is improved when a strain of microorganisms resistant to at least two different proline analogues is cultured. An improved strain of Brevibacterium ammoniagenes, designated ATCC No. 39101, has been isolated by selective culture in the presence first of L-azetidine-2-carboxylic acid then 3,4-dehydro-DL-proline, which has an altered genetic structure with respect to the L-proline feedback mechanism, and has been found to produce L-proline in commercial quantities. |
