发明名称 Cephalosporins
摘要 Compounds of the formula <IMAGE> I wherein R1 is hydrogen or a conventional amino-protecting group, R2 is a straight or branched chain alkyl, alkenyl or alkynyl containing from 1 to 4 carbon atoms, and -(+)N 3BOND Q is a quaternary ammonio group as described herein, and nontoxic pharmaceutically acceptable salts, physiologically hydrolyzable esters and solvates thereof, as well as processes for their preparation, are disclosed. The compounds in which R1 is hydrogen are potent antibacterial agents.
申请公布号 US4525473(A) 申请公布日期 1985.06.25
申请号 US19830480602 申请日期 1983.03.30
申请人 BRISTOL-MYERS COMPANY 发明人 ABURAKI, SHIMPEI;KAMACHI, HAJIME;NARITA, YUKIO;OKUMURA, JUN;NAITO, TAKAYUKI
分类号 A61K31/545;A61K31/546;A61P31/04;C07D277/20;C07D501/46;C07D513/04;C07D519/06;(IPC1-7):A61K31/545 主分类号 A61K31/545
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