| 摘要 |
PURPOSE:The titled promotor having XII factor activating ability, shortening extremely time required for blood clotting, having stable promoting effect, comprising a cyclic organic compound wherein two neighboring carbonyl groups are in the sterically and substantially same plane. CONSTITUTION:A promotor for blood clotting comprising a cyclic organic compound [e.g., O-quinone ring-containing compound shown by the formula II (e.g., R<1>, R<2>, R<3>, and R<4> are H, hydrocarbon group, polar substituent group or polycyclic compound residue), homocyclic compound shown by the formula III, etc.]. A concentration of the compound in the blood is at least 1X10<-10>g/ml (blood). In more preferable administration, the compound is supported on a carrier having large specific surface area, and it is added to the blood in a container for testing blood.
|
