| 摘要 |
NEW MATERIAL:A compound shown by the formula I (R1 is alkyl, or aralkyl; R2 is O, or S; X, Y, and Z are H, or protecting group). EXAMPLE:2-Carbamoyl- 6-methoxy- 2',3',5'-tri-O-acetylinosine[ 2-carbamoyl- 6-methoxy-9-(1-beta-D-2,3,5-tri-O-acetylribofuranosyl)purine]. USE:An antiviral agent, and an antitumor agent. Useful as a reagent for study in nucleic acid chemistry. PREPARATION:A 2-cyano-6-substituted oxypurine nucleotide (e.g., 2-cyano-6-methoxy-2',3',5'-tri-O-acetylinosine, etc.) shown by the formula II is hydrolyzed with water or treated with hydrogen sulfide.
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