发明名称 Therapeutic agents
摘要 Compounds of formula I <IMAGE> in which R1 is C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, C3-7 cycloalkyl, cycloalkylalkyl or optionally substituted phenyl; R2 is H or C1-3 alkyl; R3 and/or R4 are H, formyl, C1-3 alkyl, C3-6 alkenyl, C3-6 alkynyl, C3-7 cycloalkyl or R3 and R4 together with the nitrogen atom form a heterocyclic ring system; R5 and/or R6 are H, halo, CF3, C1-3 alkyl, C1-3 alkoxy, C1-3 alkylthio or R5 and R6 together with the carbon atoms to which they are attached form a second benzene ring show therapeutic activity in the treatment of depression. Pharmaceutical compositions and processes for preparing compounds of formula I are disclosed.
申请公布号 US4522828(A) 申请公布日期 1985.06.11
申请号 US19820365285 申请日期 1982.04.05
申请人 THE BOOTS COMPANY PLC 发明人 JEFFERY, JAMES E.;KOZLIK, ANTONIN;WILMSHURST, ERIC C.
分类号 C07D295/06;A01N33/02;A61K31/135;A61K31/16;A61K31/165;A61K31/40;A61K31/435;A61K31/495;A61P25/24;A61P25/26;C07C29/147;C07C33/50;C07C45/00;C07C45/42;C07C45/44;C07C49/237;C07C49/567;C07C57/46;C07C61/40;C07C67/00;C07C209/00;C07C209/28;C07C209/40;C07C209/48;C07C209/52;C07C209/56;C07C209/58;C07C211/25;C07C211/26;C07C213/00;C07C217/74;C07C231/00;C07C231/02;C07C231/08;C07C231/10;C07C231/12;C07C233/03;C07C233/05;C07C233/13;C07C233/18;C07C313/00;C07C323/32;C07D207/06;C07D211/70;C07D295/073;C07D295/185;(IPC1-7):A01N33/02 主分类号 C07D295/06
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