| 摘要 |
PURPOSE:To provide a sulfur-compounded external drug for skin, containing sulfur-containing granule having a specific gravity adjusted by granulation treatment, storable stably without causing the degradation such as the precipitation or coagulation of sulfur, and useful for the prevention and remedy of pimple and the reducive bleaching of the skin. CONSTITUTION:Sulfur is granulated to obtain sulfur-containing granule having a specific gravity of 0.7-1.6, and the granules are added to an external drug for skin. The granulation is carried out by mixing sulfur with a vehicle (e.g. polyethylene, lactose, etc.), optionally adding a binder (e.g. MC, CMC, etc.) to the mixture, and granulating the mixture. The sulfur-containing granule of the present invention is absolutely free from coagulation and precipitation in an external drug for skin and gives a drug having extremely high quality. |
