发明名称 BICYCLIC COMPOUNDS,THEIR PRODUCTION AND USE
摘要 New bicyclic compounds, inclusive, of salts thereof, of the formula: <CHEM> wherein R<1> and R<2> are the same or different and represents hydrogen, hydroxy or lower alkoxy, R<3> is hydrogen or lower alkyl, R<4> is hydrogen, lower alkyl, amino-lower-alkyl or acylamino-lower-alkyl, R<5> is hydrogen, lower alkyl or aralkyl which may be substituted, R<6> is hydroxyl, lower alkoxy, amino or lower alkylamino, and m and n each means 1 or 2, having inhibitory activities of angiotensin converting enzyme and bradykinin decomposing enzyme, and are useful as antihypertensive agents.
申请公布号 PH18357(A) 申请公布日期 1985.06.05
申请号 PH20090000264 申请日期 1981.10.28
申请人 TAKEDA CHEMICAL INDUSTRIES LTD. 发明人 YOSHIKAZU OKA;KOHEI NISHIKAWA;AKIO MIYAKE
分类号 C07C213/08;A61K38/00;C07K5/02 主分类号 C07C213/08
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