| 摘要 |
<p>Condensation of one of daunomycinone, 1 4-(t-butyldiphenyl-siloxy)- adriamycinone or their 4-demethoxy analogues with 3,4-di-O-acetyl-2,6- dideoxy-???-L-arabinohexopyranosyl chloride gives a mixture of two compounds which on removal of the protecting groups can be separated to give the anthracycline glycosides I and II (R1=H or OH, R2=H or OCH3> <IMAGE> The process as claimed and the compounds I (R2=H) and II are also claimed. The compounds have antitumour properties.</p> |
