发明名称 |
UN PROCEDIMIENTO PARA PREPARAR PIRIMIDONAS. |
摘要 |
<p>This invention provides a process for the preparation of pyrimidinone compounds with a group R2CH(OH)- at the 5-position thereof, wherein R2 is an optionally substituted acid-stable 5- or 6-membered nitrogen-containing heteroaryl group. The pyrimidinone ring is further substituted by a side-chain of a H1-antagonist or H2-antagonist or a precursor thereof. The compounds are convertible to 5-heteroaryl methyl compounds which are either useful H1- or H2-antagonists or precursors thereof.</p> |
申请公布号 |
ES524589(D0) |
申请公布日期 |
1985.06.01 |
申请号 |
ES19890005245 |
申请日期 |
1983.07.29 |
申请人 |
SMITH KLINE & FRENCH LABORATORIES LIMITED |
发明人 |
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分类号 |
C07D239/46;C07D401/14;(IPC1-7):C07D239/47;A61K31/505 |
主分类号 |
C07D239/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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