摘要 |
NEW MATERIAL:A compound shown by the formula (Q1 is Leu, or Met; Q2 is Arg, or Arg-Arg-Ile). EXAMPLE:H-Tyr-D-Arg-Gly-Phe-Leu-Arg-OH. USE:An economically advantageous analgesic having sufficient effect even by peripheral administration. PREPARATION:Peptide chains are extended in a solvent such as dimethylformamide, etc. by stepwise elongation method wherein amino acids are extended one after another, and finally the prepared compound is deprotected by contact reduction, etc. |