摘要 |
Compounds of the formula: <CHEM> wherein: R<1> is, e.g., hydrogen or alkyl of from 1 to 12 carbon atoms; R<2> and R<4> are independently, e.g., hydroxy or loweralkoxy; m is 1-4; R<3> is <CHEM> where n is 2-5; provided that where n = 3 or 4, the carbon chain may be unsaturated between carbons 2-3 for n = 3, and between carbons 2-3 or 3-4 or both for n = 4; the R<a>'s are independently, e.g., hydrogen or hydroxy; and the R<b>'s are independently hydrogen or loweralkyl; R<5> is hydrogen; halo; hydroxy; loweralkyl; loweralkoxy; amino; or mono- or diloweralkylamino; and a pharmaceutically acceptable salt thereof. Those compounds are inhibotors of angiotensin I converting enzyme useful as antihypertensive agents. |