摘要 |
<p>This invention encompasses prostaglandins of the formula I</p><p><Chemistry id="chema01" num="0001"><Image id="ia01" he="26" wi="83" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein X represents cis or trans -CH=CH-, -C≡-, methylene or ethylene;
<UnorderedLists id="ula01" listStyle="none"><ListItem>R, represents a cycloalkyl group of the formula
<Chemistry id="chema02" num="0002"><Image id="ia02" he="17" wi="29" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>where m is 1 to 3 inclusive</ListItem><ListItem>R<Sub>2</Sub> represents hydrogen or lower alkyl with the proviso that the sum of the carbon atoms in X and R, is 7 or less.</ListItem><ListItem>R' represents lower alkyl containing 1 to 6 carbon atoms, vinyl or ethynyl;</ListItem><ListItem>wherein R''' represents hydroxymethyl, hydroxyacetyl or -CO<Sub>2</Sub> R''''</ListItem><ListItem>wherein R"" represents hydrogen or lower alkyl containing 1 to 6 carbon atoms and the wavy line represents optional R or S stereochemistry.</ListItem></UnorderedLists></p> |