发明名称 N-substituted-5-phenyl-4,1-benzoxazepin-2(3H)-ones having therapeutic utility.
摘要 <p>Compounds of the formula &lt;CHEM&gt; wherein R1 is cyclopropylmethyl, 2-phenylethyl, aminoalkyl, cycloaminoalkyl, optionally ring-substituted phenoxyalkyl, optionally ring-substituted phenylthioalkyl, optionally ring-substituted phenylsulphinylalkyl, optionally ring-substituted phenylsulphonylalkyl, cycloalkoxyalkyl, optionally ring-substituted phenylalkyl, hydroxyalkyl, alkoxyalkyl or phthalimidoalkyl; R2 is H, alkyl or phenyl; and Y1 is H, Cl, Br, F, MO2 or CF3, can have utility as inhibitors of phospholipase A2 and thus as inhibitors of arachidonic acid cascade biosynthesis.</p>
申请公布号 EP0142361(A2) 申请公布日期 1985.05.22
申请号 EP19840307792 申请日期 1984.11.12
申请人 THE UPJOHN COMPANY 发明人 WALLACH, DONALD PINNY;SZMUSZKOVICZ, JACOB;AYER, DONALD EMORY
分类号 C07D267/14;C07D413/06;(IPC1-7):C07D267/14;A61K31/55 主分类号 C07D267/14
代理机构 代理人
主权项
地址