发明名称 |
N-[4-(3-aminopropyl)-aminobutyl]-2-( omega -guanidino-fatty-acid-amido)-2-substituted-ethanamide and salt thereof |
摘要 |
N-[4-(3-Aminopropyl)aminobutyl]-2-( omega -guanidino-fatty acid-amido)-2-substituted-ethanamides represented by the general formula <IMAGE> I wherein Y represents -(CH2-CH2-, -CH=CH or <IMAGE> R represents a hydrogen atom, an alkyl group of 1 to 4 carbon atoms which may have a hydroxyl group as substituent, or a benzyl group, and n is an integer of from 1 to 8, provided that when Y is <IMAGE> and n is 4, R represents the groups other than the hydrogen atom; a salt thereof having antitumor activity in experimental animal tumors and a process for the preparation thereof is provided.
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申请公布号 |
US4518532(A) |
申请公布日期 |
1985.05.21 |
申请号 |
US19820426372 |
申请日期 |
1982.09.29 |
申请人 |
MICROBIAL CHEM RES FOUND |
发明人 |
UMEZAWA, HAMAO;TAKEUCHI, TOMIO;KONDO, SHINICHI;IINUMA, HIRONOBU;IKEDA, DAISHIRO;NAKAMURA, TERUYA;FUJII, AKIO |
分类号 |
A61K31/16;A61P35/00;C07C67/00;C07C239/00;C07C279/14;C07D209/48;C12P13/02;(IPC1-7):C07C129/12;A61K31/155 |
主分类号 |
A61K31/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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