| 摘要 |
NEW MATERIAL:A compound shown by the formula I (R<1> and R<2> are H, lower alkyl, R<1> and R<2> form single bond; R<3>-R<6> are H, or lower alkyl; R<1>-R<6> are not H at the same time; X is N, or methylene; n is 3 or 4; dotted line part is single bond or double bond). EXAMPLE:N-[ 4-[4-(2-Pyrimidyl)-1-piperazinyl]butyl ]-1-cyclohexene-1,2-dicarboxyimide. USE:An antianxiety agent. A selective antianxiety agent having low side effect of central inhibition. PREPARATION:An acid anhydride shown by the formula II is reacted with an amine derivative shown by the formula III in an inert organic solvent such as pyridine, n-butyl alcohol, etc. under heating, to give a compound shown by the formula I . |
