摘要 |
<p>A composition for determining an analyte in a liquid sample comprises (a) a plurality of solid, reflective particles (22), (b) at least one substance (24) which comprises an extraction solvent for the analyte, and at least one substance (24) which effects a detectable response to the analyte, and (c) a binder (26) which is permeable to the analyte or a reaction product thereof in which the particles, extraction solvent and analyte-responsive substance are dispersed. Preferably, the composition is used to determine an ionic analyte by incorporating an analyte-responsive substance such as a crown ether. Test devices (10) or analytical elements include a single, integral matrix comprising a composition of the invention.</p> |