发明名称 |
2'-Substituted-spiro[benzofuran-2(3H),1'-cycloalkanes] and their analgesic and anti-depressant compositions |
摘要 |
2'-Substituted-spiro[benzofuran-2(3H),1'-cycloalkanes] and methods of praparing same are described. On the aromatic portion of the benzofuran ring, there may be a substituent or substituents including halogen, amino, lower-alkyl-substituted amino, lower alkyl, lower alkoxy, hydroxy and nitro. The substituents at the 2-position of the cycloalkane ring are -(CH2)nNR1R2 where n is 0, 1 or 2 and R1 and R2 are each independently hydrogen and alkyl of 1-3 carbons. These compounds are useful as antidepressants and analgesics. Various other compounds which are useful as intermediates for preparing the aforementioned compounds and methods for preparing same are also described.
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申请公布号 |
US4517311(A) |
申请公布日期 |
1985.05.14 |
申请号 |
US19820416446 |
申请日期 |
1982.09.13 |
申请人 |
HOECHST-ROUSSEL PHARMACEUTICALS INC. |
发明人 |
GLAMKOWSKI, EDWARD J.;JONES, DECEASED, MICHAEL C.;JONES, ADMINISTRATOR, BY HERBERT |
分类号 |
C07D307/94;(IPC1-7):A61K31/34 |
主分类号 |
C07D307/94 |
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