Process for producing a halogen-containing ethylbenzene derivative.

摘要

A process for producing a halogen-containing ethylbenzene derivative represented by the general formula:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="16" wi="70" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>where X is a halogen atom, and W is a nitrile group, a carboxyl group, a lower alkoxycarbonyl group or an amidocarbonyl group, which comprises diazotizing aniline with a nitrite in a solution mixture comprising a hydrophilic organic solvent, an aqueous mineral acid solution and a vinyl compound represented by the general formula:
<Chemistry id="chema02" num="0002"><Image id="ia02" he="8" wi="94" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>where W is as defined above, to form a benzenediazonium salt, and reacting the benzediazonium salt, without isolating it from the reaction system, with said vinyl compound in the presence of halogen ions and a copper compound as a catalyst.