| 摘要 |
Disclosed herein are novel allene-containing compounds of the formula <IMAGE> I wherein R is hydrogen, alkyl of 1 to 6 carbon atoms or a pharmaceutically acceptable salt; X is CH=CH, OCH2, CH2O, CH2S, SCH2, O or S; n is 1 or 2 but is 1 when X is CH=CH; m is 0-6; and the dotted lines represent a single or double bond. These compounds mediate leukotriene-caused physiological changes in mammals.
|
