| 发明名称 |
THE PREPARATION OF BETA-LACTAM ANTIBIOTICS |
| 摘要 |
The present invention provides a process for inversion of the absolute stereochemistry at the alpha -carbon atom of a C-6 substituent of a bicyclic carbapenem antibiotic via a phosphorus - azodicarboxylate mediated reaction. Novel azides, amines and formates are described as useful intermediates and as antibacterial agents. |
| 申请公布号 |
DE3169567(D1) |
申请公布日期 |
1985.05.02 |
| 申请号 |
DE19813169567 |
申请日期 |
1981.10.06 |
| 申请人 |
BEECHAM GROUP PLC |
发明人 |
CORBETT, DAVID FRANCIS;SOUTHGATE, ROBERT;COULTON, STEVEN |
| 分类号 |
C07D477/00;A61K31/397;A61K31/40;A61P31/04;C07D477/02;(IPC1-7):C07D487/04 |
主分类号 |
C07D477/00 |
| 代理机构 |
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