| 摘要 |
<p>New compounds useful as therapeutical agent and useful as intermediates for the preparation of other therapeutically active dihydropyridines. which new compounds are of the formula <CHEM> wherein R<1> is one or two (the same or different) substituents on the phenyl ring selected from the group consisting of lower alkyl, NO2, CN, CF3, Cl and Br; A is a straight or branched alkylene group with 2-5 carbon atoms; R<2> is <CHEM> wherein B is a straight or branched alkylene group with 2-5 carbon atoms and R<3> and R<6> are the same or different and each represents a straight or branched alkyl group with 1-5 carbon atoms, an alkylaryl group or both together are part of a 5-7membered heterocyclic ring; R<4> is a straight or branched alkyl group with 1-5 carbon atoms in which alkyl group the carbon chain is interrupted by an oxygen atom; R<5> is a lower alkyl group, or a physiologically acceptable salt or optical isomer thereof, processes for the preparation of said compounds; pharmaceutical preparations containing said compounds, a method for their therapeutical use and a new process using said compounds as intermediates.</p> |
