发明名称 PROCEDIMIENTO PARA PREPARAR IBUPROFEN CRISTALINO
摘要 <p>Ibuprofen is crystallized from a delta H>/=8 liquid such as a C1 to C3-alkanol, e.g., methanol, containing solutions thereof to obtain ibuprofen crystals which are equant (cube, sphere or grain) in shape, which ibuprofen crystals have larger average partile size, higher bulk density, lower bulk volume and improved flow properties compared to previously known bulk ibuprofen crystalline materials.</p>
申请公布号 ES530082(D0) 申请公布日期 1985.05.01
申请号 ES19820005300 申请日期 1984.02.27
申请人 THE UPJOHN COMPANY 发明人
分类号 A61K31/19;A61K9/00;A61P29/00;C07C51/00;C07C51/43;C07C57/30;C07C57/32;C07C67/00;(IPC1-7):C07C59/48 主分类号 A61K31/19
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