PREPARATION OF 6,6-DIBROMOPENICILLANIC ACID 1,1-DIOXIDE

摘要

The invention relates to a process for the preparation of 6,6-dibromopenicillanic acid 1,1-dioxide by reaction of 6-bêta-aminopenicillanic acid 1,1-dioxide with a nitrosating agent in the presence of an inorganic or strong organic acid and bromine. The invention is characterized in that the reaction is performed in the presence of an alcohol.