| 发明名称 |
Anticonvulsant sulfamate derivatives. |
| 摘要 |
<p>Sulfamates of the following formula (I):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="18" wi="70" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein X is O or CH<Sub>2</Sub> and R<Sub>1</Sub>, R<Sub>2</Sub>, R<Sub>3</Sub>, R<Sub>4</Sub> and R<Sub>5</Sub> are as herein defined have been found to exhibit anticonvulsant activity and are thus useful in the treatment of conditions such as epilepsy. Further, pharmaceutical compositions containing a compound of formula (I) as well as methods for their use and intermediates form part of the present invention.</p> |
| 申请公布号 |
EP0138441(A2) |
申请公布日期 |
1985.04.24 |
| 申请号 |
EP19840306512 |
申请日期 |
1984.09.25 |
| 申请人 |
MCNEILAB, INC. |
发明人 |
MARYANOFF, BRUCE ELIOT;GARDOCKI, JOSEPH FRANCIS |
| 分类号 |
A61F13/02;A61K31/095;A61K31/13;A61K31/135;A61K31/16;A61K31/35;A61K31/351;A61K31/70;A61P25/08;A61P27/02;A61P27/06;C07C67/00;C07C301/00;C07C305/26;C07C307/00;C07C307/02;C07C325/00;C07C381/00;C07D309/04;C07D309/06;C07D319/00;C07D493/00;C07D493/04;C07D493/14;C07H9/04;C07H11/00;C07H15/04;(IPC1-7):C07C143/00 |
主分类号 |
A61F13/02 |
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