| 摘要 |
This invention provides the compounds of the formula (I): <CHEM> and salts and esters thereof wherein R<1> is a hydrogen atom or a group selected from OH, OSO3H or a salt or a C1-4 alkyl ester thereof, OR<2>, SR<3>, OCOR<2>, OCO2R<3> or OCONHR<3>, where R<2> is a C1-6 alkyl group or an optionally substituted benzyl group and R<3> is a C1-6 alkyl group or an optionally substituted benzyl or an optionally substituted phenyl group: with the proviso that when R<1> is OSO3H or a salt or C1-4 alkyl ester thereof the C-6 and C-5 hydrogen atoms are cis. These compounds are useful antibacterial agents and also are of use as intermediates in the preparation of other carbapenems. |
