ESTER DERIVATIVES OF DEOXYFLOUROURIDINE,THEIR PROCESS OF PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM

摘要

New ester derivatives of deoxyfluorouridine of the general formula: wherein R and R40, may be identical or different, and may be hydrogen, halogen or methyl and n is 3 or 4. These derivatives are prepared by acylating a 2'-deoxy-3',5'-di-O-alkylcarbonyl-5-fluorouridine with corresponding benzoyl halides and are useful as active ingredients for anti-tumor agents, especially for oral administeration.