摘要 |
A transdermal therapeutic system for pharmaceutical agents, in particular nitroglycerin, is described and consists of a gelatin matrix which contains the agent and a transfer medium and which is applied to a protective film, where appropriate of an adhesive for fixing the system onto the skin when it is in the form of a plaster, and where appropriate of a removable protective film. The agent is present in the gelatin matrix applied to a solid, fine-particle carrier with large particle surface area. In a preferred embodiment, the system also has on the side of the polymeric matrix which faces the skin a thin film of a lipophilic substance.
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