| 摘要 |
PURPOSE:To obtain the titled substance useful as an intermediate for synthesizing vitamin E simply, by using an organic halide easily obtainable from citronellol as a raw material to prepare Grignard reagent, reacting it with alpha-methyl-beta- propiolactone. CONSTITUTION:An organic halide shown by the formula I (A and B are H, or A and B are linked to form single bond; X is halogen) is used as a raw material, and reacted with preferably 1-1.5atom equivalent metal magnesium based on the raw material compound shown by the formula I to prepare Grignard reagent. The Grignard reagent is reacted with alpha-methyl-beta-propiolactone as another raw material in the presence of a copper compound, to give a compound shown by the formula II. An amount of the lactone used is about 0.5-2mol based on 1mol compound shown by the formula I used for the preparation of the Grignard reagent, and an amount of the copper compound is preferably 0.1-10mol% based on the lactone. |
