摘要 |
A method of lowering lipid levels in a mammal involves the administration of the following N-naphthoylglycine derivatives, or a therapeutically acceptable salt with an organic or inorganic base of the first three listed derivatives: N-[[5-(trifluoromethyl)-6-methoxy -1- naphthalenyl] thioxomethyl] -N- methylglycine, N-[(5-bromo-1 - napthalenyl] thioxomethyl] -N- methylglycine, N-[[6- methoxy -5- (trifluoromethylthio) -1- napthalenyl] -thioxomethyl] -N-methylglycine, and 5-hydroxy -2-[5- (trifluoromethyl) -6- methoxy -1- napthalenyl] -3- methyl- thiazolium hydroxide, inner salt. Compositions for lowering lipid levels may contain these derivatives, optionally with other hypolipidemic agents. |