发明名称 Pyridazin-3-one derivatives
摘要 Heterocyclic compounds of the formula: <IMAGE> wherein the dotted line in the pyridazine nucleus indicates that a double bond is optional in this position, and wherein Py is a 2-, 3- or 4- pyridinyl group which is unsubstituted, or which bears one or two substituents selected from halogen, cyano, hydroxymethyl, carboxy, carbamoyl and alkyl, alkoxy, alkoxycarbonyl, alkylcarbamoyl and dialkylcarbamoyl wherein each alkyl or alkoxy has up to 4 carbon atoms, or which bears an oxygen substituent, either as an N-oxide or as an oxo substituent on the 2- or 4- carbon atom (that is, such as to form a pyridone); and acid-addition salts thereof; processes for their manufacture and pharmaceutical compositions containing them. The compounds possess cardiotonic and/or antihypertensive properties.
申请公布号 US4508721(A) 申请公布日期 1985.04.02
申请号 US19820438729 申请日期 1982.11.03
申请人 IMPERIAL CHEMICAL INDUSTRIES, PLC 发明人 HARGREAVES, RODNEY B.
分类号 A61K31/50;A61P9/12;C07D401/06;(IPC1-7):C07D237/06 主分类号 A61K31/50
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