| 发明名称 |
Quiuolizine and indolizine enzyme inhibitors |
| 摘要 |
Angiotensin I converting enzyme inhibitors A-58365 factors A, B, and C are produced by culturing Streptomyces chromofuscus NRRL 15098 under submerged aerobic fermentation conditions and are isolated and purified from the acidic filtered fermentation broth via chromatography, in particular HPLC. The factors are useful hypotensive agents.
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| 申请公布号 |
US4508901(A) |
申请公布日期 |
1985.04.02 |
| 申请号 |
US19820409763 |
申请日期 |
1982.08.19 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
MYNDERSE, JON S.;O'CONNOR, SEAN C. |
| 分类号 |
A61K31/435;A61P9/08;A61P9/10;A61P9/12;A61P43/00;C07D455/02;C07D471/04;C12N1/20;C12N9/99;C12P17/18;(IPC1-7):C07D221/02 |
主分类号 |
A61K31/435 |
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