发明名称 |
PARTIKELSUSPENSIONER FOER IMMUNOGLUTINATION. |
摘要 |
A suspension of diagnostic particles comprising antibody molecules attached to a carboxylate derivatized polymer core is provided for agglutination tests. The antibody is linked to the core through an avidin-biotin bridge. Avidin is joined by an amide bond to carboxyl groups on the core, and biotin is linked by an amide bond to amino groups on the antibody molecule. The core-bound antibody is exposed to a mixture of free biotin and biotinylated antibody to attach a controlled amount of antibody that is consistent with suspension stability prior to its use in a test and rapid cross-linking of suspended particles in the presence of antigen. |
申请公布号 |
FI842889(A) |
申请公布日期 |
1985.03.31 |
申请号 |
FI19840002889 |
申请日期 |
1984.07.18 |
申请人 |
BECTON DICKINSON AND COMPANY |
发明人 |
ROSENSTEIN, ROBERT |
分类号 |
G01N33/545;A61K39/00;A61K39/385;A61K39/44;G01N33/53;G01N33/543;(IPC1-7):G01N/ |
主分类号 |
G01N33/545 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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