发明名称 |
PROCESS FOR THE PREPARATION OF 2-AMINO-1-NAPHTHALENE SULFONIC ACID |
摘要 |
The invention relates to an improved process for the production of 2-amino-1-naphthalenesulfonic acid (Tobias acid). This improved process makes it possible to obtain Tobias acid which has only a very low content of 2-aminonaphthalene and in high space-time yield. The process starts from 2-hydroxynaphthalene and comprises the following main reaction steps: (a) the sulfonation of 2-hydroxynaphthalene to 2-hydroxynaphthalene-1-sulfonic acid (oxy-Tobias acid) with chlorosulfonic acid, in an inert organic solvent; (b) the neutralization of the liberated hydrochloric acid and excess chlorosulfonic acid still present in the reaction medium and conversion of the 2-hydroxynaphthalene-1-sulfonic acid obtained into the corresponding ammonium salt with ammonia; (c) conversion of the 2-hydroxy group into the 2-amino group by the Bucherer reaction; and (d) the subsequent precipitation of the Tobias acid with dilute sulfuric acid. |
申请公布号 |
DE3070185(D1) |
申请公布日期 |
1985.03.28 |
申请号 |
DE19803070185 |
申请日期 |
1980.12.15 |
申请人 |
CIBA-GEIGY AG |
发明人 |
PLATTNER, ERIC, PROF. DR.;STAUBLI, SEBASTIAN;VON KAENEL, FRED |
分类号 |
C07C309/47;C07C67/00;C07C301/00;C07C303/08;C07C303/32;(IPC1-7):C07C143/60 |
主分类号 |
C07C309/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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