发明名称 NEW SUBSTITUTED PIPERIDINOGUANIDINES, PREPARATION PROCESS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 Compounds having the general formula (I) wherein X1 and X2, which may be identical or different, represent hydrogen, a lower alkyl radical, a lower alkoxy radical, halogen or a trifluoromethyl radical, or form together an alkylendioxy rest. R3 is a lower alkyl radical, a lower alkenyl radical, a lower cycloalkyl radical or a heterocyclanyl radical having 5, 6 or 7 links. R4 is hydrogen, a lower alkyl radical or the acyl rest of an organic carboxylic acid; or R3 and R4 form together the alkylene rest of a nitrogen-containing heterocycle which may comprise another hetero atom. n is 1,2 or 3 and n' is 0 or 1. The compounds are in a racemic form or in an optically active form. A process for their preparation is also disclosed. The compounds of the general formula I are used as pharmaceutical compositions for the treatment of hypertensive troubles.
申请公布号 WO8501288(A1) 申请公布日期 1985.03.28
申请号 WO1983FR00185 申请日期 1983.09.19
申请人 BOUCHARA, EMILE 发明人 CORNU, PIERRE, JEAN;PERRIN, CLAUDE;DUMAITRE, BERNARD;STREICHENBERGER, GILLES
分类号 C07D211/26;C07D211/58;C07D405/06;(IPC1-7):C07D211/26;A61K31/445 主分类号 C07D211/26
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