CARBOXYALKYL DIPEPTIDES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

The compounds of the present invention are compounds of the formula and the pharmaceutically acceptable esters and salts thereof wherein R<1> and R<2> independently are hydrogen or lower alkyl; the group is one of the structures II to VIII specified @ the description, one of R<3>, R<4> and R<5> is a group @ wherein Z is selected from Z<1> to Z<1><0> being as @@ in the description and the other of the groups R<3>, R<4> and R<5> are as also defined. The compounds are useful as @@hypertensive agents, in the treatment of congestive heart failure and glaucoma. Their preparation and pharmaceutical compositions are disclosed.