Process for preparing 1-substituted-1,4-benzodiazepine derivatives.

摘要

Improvement in the production of psychotropic 1- substituted-1,3-dihydro-1,4-benzodiazepin-2-ones starting from 2-(1-substituted)amino-benzophenonimines through novel intermediates of the formula:
<Chemistry id="chema01" num="0001"><Image id="ia01" he="48" wi="52" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>(wherein R is hydrogen, methyl or benzyl, R' is C<Sub>1</Sub>-C<Sub>5</Sub> alkyl or phenyl-C<Sub>1</Sub>-C<Sub>5</Sub> alkyl, X and Y each is hydrogen or halogen and n is an integer of 1 to 2) with economical and industrial advantage.