发明名称 |
Polyoxypropylene-polyoxyethylene block polymer based adjuvants and vaccines using them. |
摘要 |
<p>An adjuvant composition comprising: an immunopotentiating amount of an immunostimulating glycopeptide; a multi-phase-forming amount of a non-toxic polyoxypropylene-polyoxyethylene block polymer in an amount of 0.2 to 49% by volume (v/v); a multi-phase-stabilizing amount of a glycol ether-based surfactant in an amount between 0.05 to 2.5% by volume (v/v); optionally a metabolizable, non-toxic oil in an amount between 1 to 30% by volume (v/v); and buffered isoosmotic saline in a quantity sufficient to make volume. This composition can be mixed with an antigen for administration as a vaccine to a bird or mammal.</p> |
申请公布号 |
EP0135376(A2) |
申请公布日期 |
1985.03.27 |
申请号 |
EP19840305687 |
申请日期 |
1984.08.21 |
申请人 |
SYNTEX (U.S.A.) INC. |
发明人 |
ALLISON, ANTHONY CLIFFORD;BYARS, NOELENE ELVA |
分类号 |
A61K9/00;A61K9/107;A61K39/39 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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