发明名称 A METHOD OF PREPARING LIPOSOMES AND LIPOSOMAL COMPOSITIONS
摘要 The invention relates to the preparation of aerosol compositions. The invention provides a method for the preparation of liposomes in which at least two separate components are brought together under pressure, a first component comprising water and a second component comprising a lipid material. The components are then passed as a mixture under pressure through a nozzle or other arrangement to produce an aerosol spray containing liposomes. In addition, at least one of the first or second components preferably includes a separate active material. The invention also provides a pack for use in preparing a liposomal aerosol comprising at least a first and a second chamber, one chamber containing a first component comprising water and the other chamber containing a second component comprising a lipid material, and one or both of the chambers and/or a third chamber including a propellant material. The pack also includes an arrangement for dispensing as a spray a mixture of the first and second components fed from their respective chambers under pressure developed by the propellant material or materials.
申请公布号 ZA8406064(B) 申请公布日期 1985.03.27
申请号 ZA19840006064 申请日期 1984.08.06
申请人 STERLING DRUG INC. 发明人 ALASTAIR RODERICK ROSS;GEORGE CONWAY GILROY;JOHN GERARD MCGURK
分类号 A61K8/02;A61J3/00;A61K8/14;A61K8/34;A61K9/00;A61K9/12;A61K9/127;A61K39/395;A61M15/00;C09K3/00;C09K3/30 主分类号 A61K8/02
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