| 摘要 |
NEW MATERIAL:A dihydropyridine derivative shown by the formula I (R<1>-R<3> are aryl; R<4>-R<6> are lower lakyl; m is 2, or 3; n is 1, or 2; A is alkylene). EXAMPLE:1,4-Dihydro-2,6-dimethyl-4- ( 3-nitrophenyl )-3,5-pyridinedicarboxylic acid 2-[4-(2,2-diphenylethyl)-1-peperazinyl]ethyl methyl. USE:A drug having peripheral vasodilating action, vasodilating action on coronary artery, cerebrovascular vasodilating action, etc. Having high effect and durability. PREPARATION:A compound shown by the formula II is reacted with a compound shown by the formula III and a compound shown by the formula IV in a solvent such as methanol or dioxane to give a compound shown by the formula I . |
