摘要 |
PURPOSE:To produce novel substance, agalactin, which is a novel anti-influenza- virus substance, by culturing a Streptococcus B-group II-type strain, and extracting from the cultured cells. CONSTITUTION:Known Streptococcus B-group II-type strain is cultured in known Tod-Hewitt medium, etc., the bacterial cell is treated with N-acetylmuramidase, and the water-soluble fraction is collected to obtain the agalactin. Agalactin has the following physical properties. Appearance, white powder; molecular weight, 200,000-500,000; UV-absorption spectrum, shoulder at 205nm; color reactions, positive to anthrone, Bayer, diphenylamine-acetic acid, and Molish reactions, and negative to thiobarbituric acid reaction; solubility, easily soluble in water, slightly soluble in ethanol and methanol, and hardly soluble in chloroform, acetone and benzene. |