BICYCLIC PROSTAGLANDINS AND PROCESS FOR THEIR PREPARATION

摘要

This invention relates to a compound of formula (I) (I) < IMG > wherein R is a member selected from the group consisting of (a) a free or esterified carboxy group; (b) < IMG >, wherein each of the R' groups, which are the same or different, is C1-C6 alkyl or phenyl; (c) -CH2OH; (d) < IMG > wherein Ra and Rb are independently selected from the group consisting of hydrogen, C1-C6 alkyl, C2-C6 alkanoyl and phenyl; (e) a radical < IMG > ; (f) < IMG > ; Z1 is hydrogen or halogen; p is zero or an integer of 1 to 7; q is 1 or 2; R1 is hydrogen3 hydroxy, C1-C6 alkoxy, ar-C1-C6-alkoxy, acyloxy; Y is a member selected from the group consisting of -CH2CH2-, < IMG >, < IMG > (cis) and < IMG > (trans), wherein Z2 is hydrogen or halogen;